An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer.

As shown in Figure 5D , although the high dose regimen showed a trend towards reduced lung metastases, no significant difference was observed in the degree of lung metastasis in animals receiving low or high Cmpd-1 and the vehicle controls.

also in 53,322 other papers

Cmpd-1 was effective on established tumor growth inhibition at the harvest time point (day 43) (p<0.01), but did not achieve significance over the entire treatment period by RM-ANOVA.

also in 1,397 other papers