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Adaptive evolution of the lactose utilization network in experimentally evolved populations of Escherichia coli.

PLoS Genet · 2012 · PMC3257284 · PMID 22253602

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a strong trendno p-value reported
We again saw a strong trend toward an increase in lac expression with 40 of 46 clones having a mean reporter expression level greater than the ancestor.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.