Although on average there appeared to be less relative NSE and GFAP protein in shKLC1-1 compared to control differentiation cultures, this trend did not reach statistical significance (p = 0.13 and p = 0.10, respectively; Figure 3B–C ), indicating that the proportions of neurons and glia within control and shKLC1-1 PA6 differentiation cultures were not different.
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Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism.
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