Barely Significant
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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega.

Mol Syst Biol · 2011 · PMC3261699 · PMID 21988835

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a clear trendno p-value reported
Once you get near 1000 or more sequences, however, a clear trend emerges.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.