The increased ERK1/2 phosphorylation observed in MCF-7 cells failed to reach statistical significance ( P = 0.06 ( n = 3)) (Figure 5b ), although significance was reached for the T47D cells ( P ≤ 0.05 ( n = 3)) (Figure 5c ).
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erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines.
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