Genomic and phenotypic analysis of BRCA2 mutated breast cancers reveals co-occurring changes linked to progression.

Looking separately at each of the two BRCA2 phenotypic subgroups (luminal and basal/TNP), a clear trend toward deletion at the BRCA2 locus emerged for the luminal types of BRCA2 tumors, in particular, in the more-proliferative luminal B type (Figure 2a ).

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