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Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy.

J Transl Med · 2012 · PMC3268093 · PMID 22236378

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Mitomycin C injection alone only led to tumor stagnation and therapeutic effects did not reach statistical significance when compared to PBS-treated controls.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.