ESR1, HK3 and BRSK1 gene variants are associated with both age at natural menopause and premature ovarian failure.

Orphanet J Rare Dis · 2012 · PMC3275465 · PMID 22248077

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nominally significantno p-value reported

Results Three SNPs - rs2278493 in HK3, rs2234693 in ESR1 and rs12611091 in BRSK1 - showed nominally significant association with POF.

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