showed a trendP = 0.08
A meta-analysis by Heyland et al [ 3 ] showed a trend toward reduced infectious morbidity (relative risk [RR] 0.66; 95% confidence interval [CI] 0.36–1.22; P = 0.08) and mortality (RR 0.52; 95% CI 0.25–1.08; P = 0.08) with early EN.