Clinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant Streptococcus pneumoniae: an observational study.

BMC Infect Dis · 2011 · PMC3276609 · PMID 22103652

Europe PMC DOI

hedged sentences

0.1400

closest p · 2.8× alpha

0.1400

boldest claim

The sentences

an increasing trendp = 0.14not close (p > 0.1)

The proportion of isolates resistant to penicillin ranged from 13 to 19% over the 10-year period, without evidence of an increasing trend (χ 2 for trend, p = 0.14) (Table 1 ).

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did not reach statistical significanceno p-value reported

In separate multivariable models for patients <15 years versus patients ≥ 15 years of age, mortality was significantly higher among patients < 15 years with penicillin-resistant isolates (adjusted HR 1.22, 95% CI 1.04 to 1.43), while the association did not reach statistical significance among older patients (adjusted HR 1.22, 95% CI 0.96 to 1.56).

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