Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients.

PLoS One · 2012 · PMC3283709 · PMID 22363760

Europe PMC DOI

hedged sentences

0.0380

closest p · 0.8× alpha

0.2300

boldest claim

The sentences

marginally significantp = 0.038actually significant

A marginally significant relationship could be detected for past history of gynaecological operations (IHC: p = 0.038, ELISA: p = 0.099), hormone replacement therapy (ELISA: p = 0.097) and alcohol intake (IHC: p = 0.098).

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showed a trendp = 0.23not close (p > 0.1)

In contrast to previous literature on endometrioid endometrial cancers, SFRP4 expression was similarly distributed in all histological subtypes of ovarian cancer ( Figure 4 A ), although in plasma, patients with endometrioid ovarian cancers showed a trend towards higher SFRP4 expression (N.S. p = 0.23; Figure 4 C ).

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of borderline significanceno p-value reported

However, this is of borderline significance as the sample size for breastfeeding was rather small.

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