Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data.

BMC Proc · 2011 · PMC3287841 · PMID 22373309

Europe PMC DOI

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closest p · 1.0× alpha

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only marginally significantp = 0.05actually significant

We checked the correlation between MAF and effect size ( β ) of causal variants for Q1 and Q2 and found that correlation for Q1 (−0.17) is not significantly different from 0 ( p = 0.3), whereas correlation for Q2 (−0.23) is only marginally significant ( p = 0.05).

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