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IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci.

J Neuroinflammation · 2012 · PMC3293042 · PMID 22248039

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As in WT-mice, WT-chimeras and IFNγR peri KO mice tended to exhibit higher Treg:Th17 ratios compared to IFNγRKO-chimeras and IFNγR CNS KO mice; however these differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.