Fewer 5αRI patients had proven extracapsular extension than controls, but this difference did not reach statistical significance (p=0.13).
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Prostate cancers detected during 5α-reductase inhibitor use are smaller, de-differentiated, but confined when compared to controls.
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0.1300
0.1700
The sentences
Overall, patients on 5αRI drugs diagnosed with cancer had a higher likelihood of having a high grade tumor, but this difference did not quite reach statistical significance (Gleason 7-10: 77% vs. 64%, p=0.17; Gleason 4+3-10: 45% vs. 30%, p=0.13).