Perilipin 2 (PLIN2)-deficiency does not increase cholesterol-induced toxicity in macrophages.

PLoS One · 2012 · PMC3299742 · PMID 22427949

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highly significantno p-value reported

Among the treatments, the effect of 7-KC was highly significant.

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did not reach statistical significanceno p-value reported

Treatment with acLDL+ACATi increased the rate of apoptosis to ∼2.6% in WT macrophages and to ∼5.6% in PLIN2-deficient macrophages, but the difference between genotypes did not reach statistical significance.

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