ORC has been seen to act in synergy with heparin; although adhesion reduction was observed in human studies, it did not reach statistical significance.[ 9 ] Seprafilm ® Is composed of modified hyaluronic acid and carboxymethylcellulose, and has been shown in gynecological studies, and specifically in myomectomy, to be effective in reducing postoperative adhesions.[ 10 ] However, it is rather difficult to use in laparoscopy as the sheets are firm and non-compliant.
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