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A phase 1 trial of recombinant human IL-21 in combination with cetuximab in patients with metastatic colorectal cancer.

Br J Cancer · 2012 · PMC3305963 · PMID 22315057

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A clear drop in T-helper cells (CD45+/CD3+/CD4+, 403 vs 310 cells μ l −1 , P =0.0876) were also observed, but this did not reach statistical significance.

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