Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.

PLoS One · 2012 · PMC3306393 · PMID 22438931

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failed to reach statistical significanceno p-value reported

There were trends toward improvement in both DASI score (increased score) and BNP (reduced concentration), although these changes failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.