Sex differences in mechanisms and outcome of neonatal hypoxia-ischemia in rodent models: implications for sex-specific neuroprotection in clinical neonatal practice.

Overall, evidence suggests that among infants at risk for HI, females may be at a quite significant advantage as compared to their male counterparts who are two times more likely to experience prenatal anoxia, hemorrhage, and infection, and 1.8 times more likely to suffer cerebral birth trauma [ 26 – 28 , 30 ].

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