BALB/c-Fcgr2bPdcd1 mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis.

Urine volume per void of AUAb-negative DKO mice showed slight and transient decrease compared to WT, but did not reach statistical significance except on the weight-adjusted data at 10-week-old ( Fig. 4A middle), suggesting that presence of AUAb had greater impact on the bladder function than the genetic modification itself.

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