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Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis.

PLoS One · 2012 · PMC3308971 · PMID 22448244

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showed a trendno p-value reported
One cohort study showed a trend for metformin users to have a higher risk of cancer in the first 2 years of follow-up.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.