Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.

29 After combining subjects with any of the fast progress genotypes to a FastP status, we observed a moderately significant contribution of the FastP signature in a subset of MCI patients with lower baseline CSF-Aβ 1−42 levels (<192 ng ml −1 ), suggesting that the signature may be additive to the known CSF biomarkers such as CSF Aβ 1−42 .

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