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Post-Aire maturation of thymic medullary epithelial cells involves selective expression of keratinocyte-specific autoantigens.

Front Immunol · 2012 · PMC3310317 · PMID 22448160

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There was a substantial reduction of all four epidermal markers at the mRNA level as well as of CK6 and involucrin at the protein level in the Aire-deficient mice; whereas the changes for protein levels of CK10 and LEKTI in the Aire-deficient mice did not reach statistical significance (Figures 2 A,B).

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