The increase mRNA levels of B 2 R, ICAM-1, eNOS and VEGF-A did not reach statistical significance in STZ-diabetic retinae, yet LF22-0542 treatment abolished to control values this trend.
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Ocular application of the kinin B1 receptor antagonist LF22-0542 inhibits retinal inflammation and oxidative stress in streptozotocin-diabetic rats.
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