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Circulating unmetabolized folic Acid: relationship to folate status and effect of supplementation.

Obstet Gynecol Int · 2012 · PMC3317000 · PMID 22529856

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The proportion of women with detectable levels of unmetabolized folic acid increased from 65% to 100% after twelve weeks of supplementation ( P < 0.05); however, the increase in concentrations did not reach statistical significance and the effect was not sustained.

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