Based on the luciferase assay, the residues shown to be significant (less than 20%) for Mal function deficiency are shown in red, moderately significant (greater than 20%, less than 50%) for Mal function deficiency in sky blue, and non-significant (greater than 50%) for Mal function deficiency in brown.
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Structural insights into TIR domain specificity of the bridging adaptor Mal in TLR4 signaling.
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