Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.

PLoS Genet · 2012 · PMC3330116 · PMID 22532803

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

nominally significantP = 0.05actually significant

In the overall set of 44 twins, we replicated 184 a-DMRs (38%) with the same direction of effect at a nominally significant threshold (P = 0.05).

also in 7,732 other papers

an overall trendno p-value reported

We found significant negative correlations between methylation and gene expression in the set of a-DMR genes ( Figure 4B ), and an overall trend towards low levels of expression at a-DMR genes.

also in 4,871 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.