Survey of human mitochondrial diseases using new genomic/proteomic tools.

Genome Biol · 2001 · PMC33397 · PMID 11423010

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moderately significantno p-value reported

The pathogenic mutation of arginine to histidine at this position represents a moderately significant divergence in sequence, substituting an imidazole group for a guanidino group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.