Insulin signaling mediates sexual attractiveness in Drosophila.

The Akt RNAi perfuming results were consistently more variable than those obtained using transgenic animals directly, and a strong trend was consistently observed ( Figure 2C ).

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There was a highly significant negative correlation between CHC changes in chico mutant flies and InR over-expressing animals ( Figure S1C ), with overexpressing females exhibiting greater levels of 7-T, 9-P, 7,11-PD, and 7-P and reduced levels of 2-MeC 26 , 5,9-HD and 7,11-ND ( Figure S2 , Table S1 ).

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