Association of human leukocyte antigen with interstitial lung disease in rheumatoid arthritis: a protective role for shared epitope.

PLoS One · 2012 · PMC3346749 · PMID 22586441

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did not reach statistical significanceno p-value reported

The difference did not reach statistical significance, because the strong linkage disequilibrium between DRB1*16∶02 and DQB1*05∶02 causes the low frequency of DRB1*16∶02 in the patients without DQB1*05∶02 and that of DQB1*05∶02 in the patients without DRB1*16∶02 .

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