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Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease.

Oxid Med Cell Longev · 2012 · PMC3347750 · PMID 22577490

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ER degradation-enhancing α -mannosidase-like 1 (EDEM) and protein kinase inhibitor p58 (P58IPK) mRNA transcripts were also elevated in the ALD group, but the intergroup differences failed to reach statistical significance due to the large within group variances.

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