Interval mapping on the full data set revealed a single region of genome-wide highly significant linkage on chromosome 7 that can explain approximately 10% of the variance in this cross ( Figure 4 ).
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The classical pink-eyed dilution mutation affects angiogenic responsiveness.
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Table S1 Markers showing near-significant and significant association with bFGF-induced corneal neovascularization in the initial C57BL/6J×SJL/J F2 cross.