Genetic variation in the β2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults.

PLoS One · 2012 · PMC3356289 · PMID 22624056

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

1.8%), although this did not reach statistical significance (OR 1.96 [95% CI 0.88–4.39]; p = 0.09).

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a statistical trendno p-value reported

A statistical trend toward lower use of non-selective beta-blockers and higher use of selective beta-blockers was observed in the meningitis cohort compared to the general population corrected for age (non-selective beta-blockers 0.9 vs. 1.8%; OR 1.96 [95% CI 0.88–4.39]; p = 0.09; selective beta-blockers 15.2% vs. 12.9%, OR 0.83 [95% CI 0.67–1.02], p = 0.08) [18] .

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