showed a trendp=0.005
At baseline (24 h after transfection, prior to wounding), cells overexpressing uPAR showed a trend towards decreased pro-MMP-2 and increased pro-MMP-9 levels by zymography ( figure 5G ), which was significant in the MMP-9 activity assay (p=0.005 active MMP-9, p<0.001 total MMP-9, figure 5H ).