Herpes simplex virus-2 glycoprotein interaction with HVEM influences virus-specific recall cellular responses at the mucosa.

Foxp3 + CD4 + Tregs were detected at a lower frequency in vaginal mucosa of mice primed with HSV-2(333)/Δ7-15- β gal compared to mice primed with HSV-2(333)/gD- β gal ( Figure 5 ); however, this difference did not reach statistical significance.

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