Influence of prenatal arsenic exposure and newborn sex on global methylation of cord blood DNA.

PLoS One · 2012 · PMC3360698 · PMID 22662134

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closest p · 1.0× alpha

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boldest claim

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borderline significantp = 0.05actually significant

Sex-specific linear regression analyses, while not reaching significance level of 0.05, indicated that the associations between As exposures and Alu, LINE-1 and LUMA were positive among male newborns (N = 58) but negative among female newborns (N = 43); tests for sex differences were borderline significant for the association of cbAs and mbAs with Alu (p = 0.05 and 0.09, respectively) and for the association between maternal uAs and LINE-1 (p = 0.07).

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did not reach statistical significanceno p-value reported

Although the associations did not reach statistical significance, arsenic exposure and DNA methylation were positively associated in males and inversely associated in females.

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