Attenuated EAN in TNF-α deficient mice is associated with an altered balance of M1/M2 macrophages.

From day 7 p.i., the clinical severity was significantly milder in the anti-TNFR1-treated group than in the control group, except on day 11 p.i., when the difference did not reach statistical significance (Mann-Whitney u-test, Figure 8 ).

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