Smoking and adipose tissue inflammation suppress leptin expression in Japanese obese males: potential mechanism of resistance to weight loss among Japanese obese smokers.

Tob Induc Dis · 2012 · PMC3364847 · PMID 22373492

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showed a trendno p-value reported

Although 10 nM of nicotine showed a trend suppressing leptin gene expression in adipocytes co-cultured with macrophages, the difference was not statistically significant (data not shown).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.