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A novel device reduces anal pain after rubber band ligation: a randomized controlled trial.

Tech Coloproctol · 2012 · PMC3368112 · PMID 22527920

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Its use tended to decrease the analgesic requirement; however, this effect failed to reach statistical significance due to the small sample size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.