Expression of the Aldo-Ketoreductases AKR1B1 and AKR1B10 in Human Cancers.

While no significant associations of patient survival with AKR1B10 expression were observed, it is noteworthy that in the solid tumors where AKR1B10 is most highly over-expressed, namely liver cancer and squamous cell lung carcinoma, there is a strong trend for AKR1B10 over-expression predicting longer patient survival (Figure 3 C).

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