AAV2-mediated combined subretinal delivery of IFN-α and IL-4 reduces the severity of experimental autoimmune uveoretinitis.

PLoS One · 2012 · PMC3369876 · PMID 22685550

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did not reach statistical significanceno p-value reported

Subretinal injection of both AAV2.IL-4 and AAV2.IFN-α showed a stronger inhibitory effect on EAU activity as compared with AAV2.IFN-α administration alone (p<0.0001) and a trend of increased inhibition when compared with AAV2.IL-4 alone, although the difference did not reach statistical significance.

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