Oxytocin and vasopressin are dysregulated in Williams Syndrome, a genetic disorder affecting social behavior.

The longitudinal changes in AVP exhibited similar but weaker trends, which did not reach statistical significance, for greater variability and greater average increases in WS versus TC ( Table 2 , Fig. 5 ).

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Therefore, it is significant that, despite this variation, the effect sizes of exaggerated responses of OT between WS and TC are highly significant, even in the presence of behavioral variation within the WS cohort.

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We also observed a decreasing trend in systolic blood pressure in response to music in WS but not TC (SOM Fig.

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