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Cost-effectiveness of dabigatran versus genotype-guided management of warfarin therapy for stroke prevention in patients with atrial fibrillation.

PLoS One · 2012 · PMC3382133 · PMID 22745801

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showed a trendno p-value reported
An analysis of the RE-LY data showed a trend of better relative performance for dabigatran in centers with lower mean patient-time in therapeutic range (TTR), despite the differences in stroke and intracranial bleeding among centers in different TTR quartiles were not statistically significant [4] .

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