Functional anomalies in healthy individuals with a first degree family history of major depressive disorder.

fMRI data (Table 3 ) Contrast F > N MDD patients exhibited smaller activation than healthy controls (HC) in the left middle cingulum (T = 3.82, P = 0.041, FWE corrected for multiple comparisons) and left insula (T = 4.19, P < 0.001, uncorrected), which also showed a trend for significance after correction for multiple comparisons ( P = 0.072) (Figure 1 ).

also in 53,322 other papers