Arp2/3 complex-dependent actin networks constrain myosin II function in driving retrograde actin flow.

J Cell Biol · 2012 · PMC3384413 · PMID 22711700

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In contrast, after CK666 addition (50 μM) in the continued presence of blebbistatin there was a clear trend of slower actin turnover after Arp2/3 complex inhibition with integrated ROI actin intensity falling to only 66.6 ± 4.2% over the same period ( Fig. 5 G , magenta line).

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