Pharmacological approaches to the treatment of complicated grief: rationale and a brief review of the literature.

36 Although results for each group were only marginally significant, they reported that in the full sample (n=95), even after controlling for covariates (age, gender, race, and psychiatric comorbidity), participants who were prescribed a stable dose of antidepressant during the trial were more than two times more likely to be treatment responders (“very much improved” and or “much improved” on the CGI-I scale) than those who were not (adjusted odds ratio=2.7, 95% confidence interval (CI)=1.1 - 6.8).

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