Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome.

PLoS One · 2012 · PMC3387159 · PMID 22768046

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Predictors of Discontinuation for Each Immunomodulatory Treatment In the univariable analysis of the predictors of discontinuation for each of the four IMDs, female sex was found to be a significant predictor of increased rate of discontinuation of IM and SC IFNβ-1a, with a strong trend for IFNβ-1b ( Table 3 ).

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