The total vessels staining for TGF-β1 in the Rbm correlated reasonably strongly with number of vessels stained for vascular endothelial growth factor (VEGF, measured in our previous study [24] ) only in the S-COPD group, but this did not reach statistical significance (r = 0.6, p = 0.1), but is probably a type 2 error.
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Vessel-associated transforming growth factor-beta1 (TGF-β1) is increased in the bronchial reticular basement membrane in COPD and normal smokers.
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