L-DOPA changes spontaneous low-frequency BOLD signal oscillations in Parkinson's disease: a resting state fMRI study.

Front Syst Neurosci · 2012 · PMC3389385 · PMID 22783172

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.055so close (0.05 < p ≤ 0.1)

Motor symptoms measured by UPDRS only showed a trend to be worse in PD OFF than PD ON [ t (23) = −2.0, p = 0.055], and pegboard performance for the more affected side was significantly worse for PD OFF than PD ON [ t (23) = −2.61, p < 0.05] but not for the less affected side.

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marginally significantp = 0.08so close (0.05 < p ≤ 0.1)

A paired t -test comparing the average power of the precentral gyrus ROI between PD OFF and PD ON showed a marginally significant difference with decreased power in PD ON compared to PD OFF [ t (23) = 1.81, p = 0.08, Figure A2 ].

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