Although there was a possible trend towards decreased IgG1, there was no reduction in the concentrations of either IgG2b or IgG2c (the homolog of IgG2a found in C57BL/6 mice) in the groups treated with EP67 compared to the non-treated control animals.
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Innate immune induction and influenza protection elicited by a response-selective agonist of human C5a.
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The sentences
Although the total anti-influenza IgG response was lower in all groups that exhibited significant protection from influenza-induced weight loss, this decrease did not reach statistical significance.